Looking for the Best Digestive Enzymes available to buy right now on Amazon but don’t want to have to do all the research on the pros and cons of the different types of Digestive Enzymes?
Pop Expert have put together this list of the top 10 selling Digestive Enzymes on Amazon – sorted by overall popularity and positive consumer reviews.
The Pop Expert list of top selling Digestive Enzymes is the ideal place to start when you are trying to find the Best Digestive Enzymes for your neeeds.
Popular Digestive Enzymes on Amazon
Details on the Best Digestive Enzymes
On Sale!Bestseller No. 1
Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 60 CT
- Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack! Same great product you love, with a new look. Packaging May Vary!
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort. One Month Supply
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured w/ love & care in the USA with strict quality control - using imported & domestic ingredients. No Refrigeration Needed
$23.52
−$3.55
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On Sale!Bestseller No. 2
NOW Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain, Super Enzymes,90 Capsules
- SUPPORTS HEALTHY DIGESTION*: NOW Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion.* Take one capsule with a meal
- BREAKS DOWN FATS, CARBS, AND PROTEINS*/OPTIMIZES NUTRIENT AVAILABILITY*: Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein*
- CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Made without Gluten, Keto Friendly
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
- Packaged in the USA by a family owned and operated company since 1968
$23.99
−$11.49
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On Sale!Bestseller No. 3
Zenwise Health Digestive Enzymes for Gut Health & Bloating Relief - Multi Enzymes Digestion Supplement with Probiotics, Bromelain & Papaya for Digestive Health Support - Men & Women - 60 Count
- 3-in-1 Formula – A potent blend of lab-proven enzymes, including bromelain and papaya, clinically proven probiotics, and prebiotics work synergistically to break down proteins, fats, and carbs while restoring digestive flora balance for optimal nutrient absorption and digestion. This formula helps maintain digestive wellness and promotes regularity.
- Fast-Acting Enzymes – Featuring powerful enzymes like bromelain (from pineapple) and papain (from papaya), this blend starts working immediately to break down food up to 39% more completely, easing indigestion for rapid, noticeable relief.
- Proven Probiotics – Guaranteed to arrive alive and work within hours in the small intestine where 90% of nutrient absorption occurs, helping support overall digestive health.
- Gas & Bloating Relief – Targeted enzymes, including bromelain and papaya, work with beneficial microflora to ease uncomfortable bloating, reduce gas, and soothe digestive discomfort naturally.
- Plant-Based Formula – Pure vegetarian enzymes, including bromelain and papain, combined with prebiotic fiber nourish your microbiome while supporting healthy digestion and immune function. Take 1 capsule before your meal to experience digestive delight.
$19.97
−$3.00
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Bestseller No. 4
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules
- Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption; supports digestion*
- Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides and disaccharides; assists with dairy, fiber, and protein digestion*
- Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
- Dairy Enzyme Blend: This vegetarian enzyme blend supports digestion of dairy, sugar, lactose, and certain complex carbs; supports relief from occasional gas or bloating
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
On Sale!Bestseller No. 5
Source Naturals Essential Enzymes 500mg Bio-Aligned Multiple Enzyme Supplement Herbal Defense for Digestion, Gas, Constipation & Bloating Relief - Supports A Strong Immune System - 60 Capsules
- Digestive Aid that aids the body’s natural digestive process, helping to maximize the body’s utilization of the nutrients in the diet while supporting digestive comfort.
- Formulated to support optimal nutrient utilization, digestive health, and digestive comfort.
- Delivers 8 enzymes that break down every food type: proteins, fats, milk sugar, fiber, and carbohydrates.
- Works in a wide range of pH levels
- Convenient capsules can be opened and sprinkled over food if desired. DO NOT sprinkle on hot food.*
$10.50
−$1.93
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Newest Digestive Enzymes
New
Digestive Enzymes Supplement with 100 Billion CFU Organic Probiotic & Prebiotic – Multi-Enzyme Formula for Women & Men – Supports Digestive & Gut Health, Aids Protein, Carb & Dairy Digestion, 60 Caps
- Essential Supplement for Daily Gut & Digestive Health - Proriginal Digestive Enzymes feature a powerful 3-in-1 blend of fiber supplement, 100 billion CFU of shelf-stable probiotics(especially Acidophilus Probiotic), effective digestive enzymes(including Bromelain, Serrapeptase, Papaya Enzymes, etc.), and prebiotics(with enough Inulin) to better promote digestion, regularity, support bloating, and keep light and balanced—whether you’re home, work or travel. No refrigeration is needed
- Easy to Swallow for a Comfortable Daily Routine – Our size 0 vegetable capsules are small, smooth, and flavorless—easy to swallow and gentle on the stomach. They can be taken before or after meals, making them ideal for those with digestive sensitivity or busy lifestyles
- Made for Whole Family, Supports Wellness, Energy & Weight Goals - Specially formulated for adult men and women, this daily supplement supports digestive balance, natural energy production, and healthy weight management*. It features clean herbal adaptogens like Asian Ginseng and Lion’s Mane, along with L-Glutamine for gut integrity and immune support. Taken consistently, it helps maintain digestive vitality and overall metabolic health.
- Pure, Plant-based, and Safe for All Dietary Styles - This product is 100% vegan and made without gluten, dairy, soy, GMOs, or artificial fillers, making it safe for any dietary routine. It’s also third-party tested for quality, purity, and safety—ideal for those with stomach sensitivities. Temporary gas bloating is normal, keep using it for better gut cleanse and overall health
- Built for Sustainable, Long-Term Digestive Support – Formulated with gentle yet effective ingredients, this supplement is ideal for consistent daily use. Over time, it helps reinforce digestive efficiency, optimize nutrient utilization, and support a more resilient gut environment—providing a stable foundation for lasting digestive health
New
Stop Aging Now - Digestive Enzymes Plus Probiotics - CoreZyme - 60 Count
- Contains a full spectrum, high potency blend of enzymes designed to optimize digestion of fats, protein, carbohydrates and fibers, while maximizing nutrient absorption and supporting efficient elimination*
On Sale!New
Healthy Gut HistaHarmony, 60 Tablets, and HoloZyme Digestive Enzymes, 30 Capsules
- This bundle contains one box of HistaHarmony, 60 Tablets, and one bottle of HoloZyme Digestive Enzymes, 30 Capsules.
$60.49
−$6.05
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New
Papaya Enzyme, Complex Chewable Tablets, Papaya Enzymes for Digestion, Supplement, 180 Count + 7 Day Pill Organizer Included (Pack of 2)
- Papaya Enzyme, Complex Chewable Tablets, Papaya Enzymes for Digestion, Supplement, 180 Count + 7 Day Pill Organizer Included
New
Emerald Essentials Digestive Enzymes with Prebiotics & Probiotics - Bromelain & Multi Supplement for Digestive Health
- Supports digestion of proteins, fats, dairy, and carbohydrates with a comprehensive enzyme blend Includes probiotics Bacillus subtilis and Bacillus coagulans to help support microbiome balance Lactase and lipase assist with dairy and fat breakdown Peppermint and ginger root offer a gentle botanical approach to digestive support Clean formula: Non-GMO, vegan, gluten-free, and third-party tested for quality