Looking for the Best Systemic Enzymes available to buy right now on Amazon but don’t want to have to do all the research on the pros and cons of the different types of Systemic Enzymes?
Pop Expert have put together this list of the top 10 selling Systemic Enzymes on Amazon – sorted by overall popularity and positive consumer reviews.
The Pop Expert list of top selling Systemic Enzymes is the ideal place to start when you are trying to find the Best Systemic Enzymes for your neeeds.
Popular Systemic Enzymes on Amazon
Details on the Best Systemic Enzymes
Bestseller No. 1
Pure Encapsulations Systemic Enzyme Complex - Supports Muscle Recovery & Joint Health - for Immune Health* - Gluten Free & Non-GMO - 180 Capsules
- Essential Enzyme Blend: Systemic Enzyme Complex protease enzyme supplement features pancreatin, protease, serrazimes, bromelain, and papain for muscle, joint, and immune health*
- Enzyme Support: Formulated with papaya fruit and other enzymes, this blend offers impressive overall health support, supporting muscle comfort and recovery*
- Joint Health: Formula contains 250 mg of Indian frankincense (Boswellia serrata), a potent boswellia supplement for robust joint support and cartilage health*
- Suggested Use: As a dietary supplement, take 3 digestive enzyme capsules, 1-2 times daily, between meals
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs
Bestseller No. 2
MaryRuth Organics Serrapeptase Enzymes Capsules | Up to 2 Month Supply | Enzyme Supplement for High Potency Sinus Relief Pills| Tissue Health and Cellular Health | Vegan | Gluten Free | 60 Count
- Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme-enhancing vitamins and minerals to support your overall health. Encapsulated in pine-based vegan capsules | you can easily incorporate these into your routine.Serrapeptase Systemic Enzymes: This proprietary blend of enteric-coated Serrapeptase (also known as Serratiopeptidase) and a Protease blend is combined with enzyme enhancing vitamins and minerals to support your overall health. Encapsulated in pine-based vegan capsules | you can easily incorporate these into your routine.
- Multiple Benefits: Serrapeptase may help to support the body's circulatory system | healthy tissue homeostasis | and the body’s natural inflammation process. This powerful enzyme blend may support cellular | tissue | and systemic health | while promoting healthy immune activity and aiding your body in maintaining normal microbial balance.
- Advanced Enzyme Complex: 120 000 SPU Serrapeptase in each capsule. Sometimes referred to as a “super enzyme,” serrapeptase has been shown to affect the movement of immune cells, while the Protease blend works at normal cellular detoxification to efficiently digest all types of proteins. Pairing these enzymes with cofactor vitamins and minerals helps your body use the enzymes faster and more efficiently.
- Easy Efficient Absorption: This supplement is formulated to be taken systemically, not digestively. It's best to take it on an empty stomach, allowing the enzymes to support your body rather than digest your food. Adults take one capsule up to two times daily or as recommended by a physician or healthcare professional. For best results, take it on an empty stomach with a large glass of water 30-60 minutes before or 2 hours after a meal.
- For Most Lifestyles, MaryRuth's Serrapeptase Systemic Enzymes are Non-GMO and Vegan. They are Dairy-Free, Nut-Free, Gluten and Wheat-Free, Soy-Free, Nightshade-Free, and Sugar-Free. This product contains maltodextrin, which is corn-derived.
Bestseller No. 3
Bestseller No. 4
Rootcology by Dr. Izabella Wentz | Systemic Enzymes | Support Normal Tissue Repair with Turmeric and Ginger Extract | Natural Support for Healthy Healing | 60 Capsules
- Supports Joint and Tissue Health: Formulated with proteolytic enzymes to aid in maintaining healthy joints and support normal tissue repair.*
- Enhances Antioxidant Defense: Provides nutrients that contribute to the body's natural antioxidant mechanisms.*
- Two Capsules Per Day: Rootcology Systemic Enzymes contain a stronger formulation than is used in many other brands, which does not require a large number of capsules. Just two capsules per day is recommended.*
- Clean and Allergen-Friendly Formula: Free of common allergens, suitable for various dietary needs. All Rootcology products are lab tested and use pure formulas.
- Created by a Pharmacist & Thyroid Expert: Dr. Izabella Wentz, Pharm.D., FASCP is a passionate, innovative and solution focused clinical pharmacist well versed in finding and evaluating emerging research to help address her clients' unique challenges. Although trained as a pharmacist, she is an ardent champion for lifestyle interventions, which often help patients more than any medications.
Bestseller No. 5
VITÄLZYM Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules)
- Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today. Our formula contains no gluten, yeast or dairy and is designed to ensure maximum absorption into the bloodstream where it is then dispersed via your circulatory system throughout your body
- Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex. Vitalzym was designed using a scientific research process to identify nature’s miracle ingredients that include Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract
- Protect Your Health: Living well in modern times can be stressful and a source of pain at times. Vitalzym contains the most effective, purified vegan-based enzyme blend to promote healing, human bodily functions and leave you feeling clear and fresh
- Small, Easy To Swallow Gel Caps: Our advanced encapsulations deliver reliable results that offer pure, potent enzymes with reliable consistency and unrivaled absorption rates. Due to the highly effective delivery rate most people need a smaller dosage, and less doses per day
- Made In Japan: Created by a team of international scientists, Vitalzym works best when combined with exercise, proper fluid intake, and a healthy diet. It is important to be mindful of all aspects of your health. When used properly, Vitalzym can assist with cardio, lung, and immune response as well as provide joint, inflammation support and much more
Newest Systemic Enzymes
New
Atherionyxora Spike Detox – Nattokinase Supplement 10,000 FU with Serrapeptase 18,000 SPU & Bromelain 800 GDU – 3-in-1 Systemic Multi-Enzyme Formula for Heart - 360 Tablets
- 3-in-1 High-Potency Multi-Enzyme Formula: Spike Support Supplement combines Nattokinase (10,000 FU), Serrapeptase (18,000 SPU), and Bromelain (800 GDU) in a 3-in-1 multi-enzyme blend for protein breakdown, circulatory clarity, and balanced inflammatory response
- Herbal & Antioxidant Support Blend: Herbal & Antioxidant Blend with NAC, black seed, dandelion, turmeric, and quercetin, forming a comprehensive herbal antioxidant complex designed for natural antioxidant properties, gentle internal cleansing, and overall formula synergy
- High Absorption & Bioavailability: Black pepper extract combined with turmeric and quercetin in this multi-enzyme and herbal formula for efficient ingredient utilization
- Enteric-Coated Technology for Precise Release: Protects active enzymes from stomach acid, ensuring stable release in the intestines for optimal potency and systemic benefits
- Clean & Trusted Formula: Gluten-free, soy-free, and free from artificial colors or preservatives, making it suitable for those seeking a pure, high-quality supplement
New
Atherionyxora Spike Detox – Nattokinase Supplement 10,000 FU with Serrapeptase 18,000 SPU & Bromelain 800 GDU – 3-in-1 Systemic Multi-Enzyme Formula for Heart - 90 Tablets
- 3-in-1 High-Potency Multi-Enzyme Formula: Spike Support Supplement combines Nattokinase (10,000 FU), Serrapeptase (18,000 SPU), and Bromelain (800 GDU) in a 3-in-1 multi-enzyme blend for protein breakdown, circulatory clarity, and balanced inflammatory response
- Herbal & Antioxidant Support Blend: Herbal & Antioxidant Blend with NAC, black seed, dandelion, turmeric, and quercetin, forming a comprehensive herbal antioxidant complex designed for natural antioxidant properties, gentle internal cleansing, and overall formula synergy
- High Absorption & Bioavailability: Black pepper extract combined with turmeric and quercetin in this multi-enzyme and herbal formula for efficient ingredient utilization
- Enteric-Coated Technology for Precise Release: Protects active enzymes from stomach acid, ensuring stable release in the intestines for optimal potency and systemic benefits
- Clean & Trusted Formula: Gluten-free, soy-free, and free from artificial colors or preservatives, making it suitable for those seeking a pure, high-quality supplement
New
Healfree Systemic Enzyme - Advanced Formula for Total Health and Optimal Well-Being Pack of 2 (1)
- Essential Support: Helps reduce Bloating, Inflammation, Speeds up recovery time, and Supports Immune System
- We make the Enzymes: All Enzymes in our product are manufactured by our Parent company Biozyme USA which is one of the largest enzyme producers in the USA.
- Proprietary Enzyme Blend: Our Systemic Enzyme supplement features Pancreatin, Lipase, Trypsin, Chymotrypsin, Bromelain, and Beta Glucan
- Suggested Use: 3 Tablets on an empty stomach at least 1 hour before or 2 hours after a meal, twice daily
- Only The Best ingredients: All active ingredients are naturally extracted, GMO free, Gluten free, Allergen free, and Dairy free, with no artificial flavors or preservatives.
New
Trebinase: A Systemic Enzyme Blend containing Serrapeptase, Nattokinase, Seaprose Along with Digestive Enzymes. (90 Capsule Bottle/1 Month Supply)
- Trebinase 320,000 FU's Per Capsule: Trebinase contains a powerful blend of systemic enzymes, including serrapeptase, protease and nattokinase along with digestive enzymes. Trebinase is the Only 3 Capsule Per Day Systemic Enzyme on the Market.
- Promotes Healthy Blood Flow: By assisting in the breakdown of excess proteins in the blood. Trebinase helps maintain optimal blood flow throughout the body.
- Supports natural healing processes: Trebinase supports the body's natural ability to heal and recover by aiding in the breakdown of unwanted proteins, promoting tissue repair and regeneration.
- Whether you're active, aging, or simply want to feel your best, systemic enzymes like those in Trebinase can support a balanced response to the physical demands of life.
- Comprehensive Enzyme Blend: Experience the power of a nattokinase serrapeptase supplement with added seaprose and digestive enzymes for enhanced whole-body enzyme support.
New
Serrasolv 360: 90 Capsule Bottle – Advanced Systemic Enzyme Serrapeptase Supplement containing 180,000 of Enteric Coated Serrapeptase per Capsule.
- HIGH POTENCY FORMULA – 180,000 SPUs Per Capsule - Each serving of SerraSolv 360 delivers a powerful 180,000 serrapeptase units (SPUs) in a delayed-release, enteric-coated capsule—designed to bypass stomach acid and ensure maximum enzyme activity where your body needs it most. For optimal results, take 1 capsule up to 3 times daily on an empty stomach to support full-body wellness, respiratory function, and breakdown unwanted protein formations.*
- MAXIMUM POTENCY, TARGETED DELIVERY – Ordinary serrapeptase can lose its effectiveness when exposed to harsh stomach acid. That’s why SerráSolv 360 is formulated with Enteric Coated Serrapeptase, an advanced acid-resistant coating that ensures the enzyme survives the stomach and is released in the intestines where absorption is optimal—for maximum results you can feel.*
- PROTEIN-BREAKING POWER FOR TOTAL BODY SUPPORT - Serrapeptase is a proteolytic enzyme, meaning it specifically targets and breaks down non-living proteins in the body—such as excess mucus, scar tissue*, and fibrin*. This unique action helps dissolve unwanted protein-based debris that can contribute to respiratory issues, and other health concerns.*
- SUPPORTS CLEARER BREATHING & SINUS RELIEF - SerraSolv 360 helps promote healthy respiratory function by breaking down excess mucus and supporting normal sinus drainage. Its powerful enzyme action encourages open airways, clearer breathing, and a balanced immune response—making it ideal for seasonal support or everyday lung health.*
- PROUDLY MADE IN THE USA - SerraSolv 360 is manufactured in Phoenix, Arizona, in a state-of-the-art facility that follows current Good Manufacturing Practices (cGMPs) as outlined by the U.S. Food and Drug Administration (FDA)—ensuring safety, purity, and quality you can trust.*