Best Enzyme Laundry Detergent

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Looking for the Best Enzyme Laundry Detergent available to buy right now on Amazon but don’t want to have to do all the research on the pros and cons of the different types of Enzyme Laundry Detergent?

Pop Expert have put together this list of the top 10 selling Enzyme Laundry Detergent on Amazon – sorted by overall popularity and positive consumer reviews.

The Pop Expert list of top selling Enzyme Laundry Detergent is the ideal place to start when you are trying to find the Best Enzyme Laundry Detergent for your neeeds.

Popular Enzyme Laundry Detergent on Amazon

Details on the Best Enzyme Laundry Detergent

Bestseller No. 1
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads
  • Powerful Bio Enzymatic Cleaner: ACTIVE Laundry Odor Removers Boost your normal laundry detergent to effectively target Stains & Odors, not mask them like washing soda or in-wash scent boosters. It uses Lab-proven Biological Cleaning to remove laundry odor & strong smell
  • Heavy Duty Stain Remover for clothes: Our Enzyme Laundry Additive Powder is formulated for Stain Removal of dirty clothes, perfect for Funk, Grease, Armpit Sweat stain, Blood stain, Oil and more!
  • Gentle on All Fabrics: Our Fragrance Free Laundry Boost Plant-based Formula uses zero harsh chemicals. Natural enhancer for whites & colors. Even safe for pesky activewear fabrics
  • Value 64 Load Package: ACTIVE Enzyme Cleaner Concentrated 32-oz size is good for 64 Loads compared to other products with 1 lb or less
  • Compatible with all Washers & Detergents: Add ACTIVE Laundry Booster Powder to your usual detergent & cleaners! HE, Front & Top load Washer Approved. Also use as laundry soak pretreat powder in order to treat set-in stain
Bestseller No. 2
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, Laundry Stain and Odor Removing Additive For All Machines, Spray, 32 oz
  • LAUNDRY BIO-ENZYMATIC FORMULA: Helps break down and destroy tough pet stains and odors, such as urine, feces, vomit, blood, grass and drool.
  • GENTLE ON FABRICS: Perfect for use on clothing, pet beds and more—not for use on specialty fabrics, including washable silk, khaki, fluorescents, wool, suede and leathers.
  • SAFE FOR PETS AND HOME: Formulated without phosphates, parabens, sulfates and bleach, this product is safe for use around pets and home, when used as directed.
  • ODORCAPTURE 360 TECHNOLOGY: An odor neutralizing system from Nature’s Miracle, the brand you trust because it works!
  • WORKS IN ALL MACHINES INCLUDING HE: Use in addition to your laundry detergent to help loosen and remove tough pet stains and odors.
Bestseller No. 3
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads
  • Concentrated Powder Detergent: ACTIVE Pet Detergent is a Powerful, High Efficiency Compatible Odor Destroyer & Stain Eliminating Detergent. Every Scoop has a Natural Cleaning Power to Handle any Mess, Stain, or Smell left behind by your pet.
  • Suitable for all Pet Laundry: Including Pet Bed, Clothing, Leash, Harness, Blankets, Towels, Furniture Covers & More! ACTIVE is an All-in-One Laundry Detergent Compatible With All Fabric Types, Even Use on your own Clothing and Bedding that smells like your pet!
  • Bio Based Enzyme Cleaner: ACTIVE Enzyme Laundry Detergent is Formulated to Target Pesky Stains and Odors, Including Pet Urine, Cat & Dog Pee, Vomit, Slobber, Dirt, Grime, Oils and Protein Stains. ACTIVE Enzymes even get rid of Wet Dog Odor, and others stubborn scents
  • Natural & Fragrance Free: ACTIVE Pet Detergent is a Natural Laundry Stain Remover, Free of Harsh Chemicals and Gentle for Pets and Sensitive Skin. ACTIVE Actually Removes Odors rather than using scents to cover them up like some alternatives
  • Best Value 64 Loads: Compare ACTIVE Dog Laundry Detergent to liquids that take up more space with less uses. Our Value Pack Comes in a Bulk 2 Lb bag so you can Keep Your Pet Laundry Taken Care Of!
Bestseller No. 4
Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural Performance Concentrate Enzyme Booster Deodorizer - Powder Wash for Activewear Gym Apparel (90 Loads)
  • Made in USA - Our powdered detergent is scientifically formulated with all natural plant-based enzymes that remove and eliminate smells generated from sweat in fitness and gym clothes
  • Specialized Formula- The specialized laundry detergent for men's or women's athletic clothing compatible with your favorite brands activewear
  • Workout Clothes Detergent - Remove smells from workout shirts, shorts, bras, tank tops, leggings, yoga pants, uniforms, jerseys, compression underwear, jock strap, and socks
  • Plant Based - ACTIVE is free from SLS free, phosphate free, gluten-free, septic safe. Made with plant based enzymes
  • Save Money - Concentrated formula provides a bulk value of 90 loads per bag! ACTIVE laundry detergent extends your clothes lifespan and protects them for the long run!
Bestseller No. 5
Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster
  • GENTLE: Our formula is consciously formulated with 100% bio and mineral-based ingredients. We left out all the harsh chemicals, fillers, toxins, and pollutants commonly found in other boosters to create a hyperefficient, nontoxic, biodegradable formula. We only use the good stuff so your body and the environment are left as clean as your detergent.
  • EFFECTIVE: Our advanced 4-in-1 formula is the first laundry product in the US to feature a groundbreaking bioenzyme that breaks down tough-to-remove “biological” stains and odors caused by sweat, body grime, and blood. (Think ring around the collar, yellow pit stains, weird grey or yellow stains on your favorite white sheets, and other stains.)
  • ENVIRONMENTALLY FRIENDLY: At Dirty Labs - Less is More. By creating hyper-concentrated formulas, we greatly reduce our package sizes (and thus, our carbon footprint). Our packaging is made of recyclable cardboard. Our scoop is made from responsibly sourced schima superba wood. Our materials are responsibly sourced and extracted directly from nature. We examine every aspect of our product life cycles in order to achieve the safest, most sustainable solutions.
  • DIRECTIONS: Follow your washer and garment care label instructions. For best results, use with Dirty Labs Bio Laundry Detergents. For standard and HE machines. Septic Safe. 1) Use laundry detergent as you normally would. 2) Add Bio Laundry Booster to wash drum before adding clothes.
  • SPECS: 480 g = 48 loads. Free & Clear (Scent Free). Compatible with traditional and HE washers. Optimized for cold water. No synthetic ingredients. Biodegradable formula. Hypoallergenic and safe for sensitive skin. Safe for babies and pets. Cruelty-free. Vegan. No sulfates. No dyes. No parabens and preservatives. No optical brighteners. No chlorine bleach. No 1,4-dioxane. No fragrance. No CA Prop. 65 chemicals. Packaging and formula are BPA-free.

Newest Enzyme Laundry Detergent

New
The Laundress New York Stain Solution, 16 Fl Oz Stain Remover for Clothes (Pack of 2)
  • The information below is per-pack only
  • New formula made with bio-based ingredients for expert stain removal.
  • Stain targeting pretreatment for old and new stains​. For tougher stains, pour onto stained fabric, rub gently and allow to soak. Launder as normal.
  • Fragrance-Free triple enzyme blend tested on stubborn stains and dirt, including red wine, yellowed pits, makeup, grass, and coffee.
  • Suitable for use on all washable fabrics for exceptional garment care​, always test first.
New
The Laundress Activewear Laundry Detergent, 32 Oz, Marine Fragrance, 4-in-1 Enzyme Blend for Workout Performance Fabrics, Fights Sweat Odors & Stains, USDA Certified Biobased Product (90%) (Pack of 2)
  • The information below is per-pack only
  • Deep Clean to Freshen & Fight Odors: Sweat the workout, not the laundry. Our hardworking 4-in-1 enzyme blend penetrates high tech moisture-wicking performance fabrics such as nylon, spandex, cotton, and synthetics to help fight odors* and stains
  • Fragrance That Moves With You: Immerse your active gear with perfumer-crafted Marine, a bright energetic blend of bergamot and mandarin with oceanic notes. Long-lasting glamorous fragrance that goes the distance and powers you through your day
  • Keeps Fabrics Feeling Fit: The Laundress Activewear Detergent will keep your training gear, luxury athleisure, yoga sets, sports jerseys and running shorts feeling fresh and looking like new by lifting tough stains and maintaining vibrancy
  • From Studio to Street: Whether you're training for a marathon or just running errands, discover beautifully clean athletic clothing with our USDA Certified Biobased (90%) fabric care detergent made to refresh every move
New
Non-Ionic Stain Remover Spray – Powerful Stain Remover Spray & Enzyme Stain Remover with Fabric Spot Cleaner, 2026 Upgrade No Damage Laundry Pre-Treatment (Blue Bottle, Option A (308 ml))
  • Powerful Stain Remover Spray with Active Enzyme Laundry Booster – This non toxic stain remover uses non-ionic emulsifying technology to quickly break down grease, oil, food and ink, penetrating deep into fabric fibers for a thorough clean
  • Fabric Spot Cleaner & Stain Treater Spray Works as a Laundry Degreaser – Specifically formulated as a grease stain remover for clothes and best armpit stain remover, it tackles sweat, collar rings and stubborn oily marks without damaging delicate fibers
  • Sensitive Skin Stain Remover & Natural Stain Remover – An organic stain remover and eco friendly stain remover choice, free from harsh chemicals, chlorine and dyes, gentle enough for the whole family while delivering powerful cleaning performance
  • Spray and Wash Stain Remover Restores White Clothes Stain Remover Results – This laundry emulsifier spray lifts old yellowing, color transfer and set in stain remover challenges, also works as a dry cleaning spray for quick fabric refresh without a full wash
  • Fabric Spray & Travel Stain Remover for On-the-Go Freshness – Compact and ready to use, this spot cleaner saves your clothes anytime anywhere, perfect for business trips, dining mishaps or quick touch-ups between washes
New
Savon Blanc Concentrated Liquid Laundry Detergent, 1L – 99% Natural Plant-Based Marseille Soap Formula, HE Compatible, Cold Wash Effective, Gentle on Fabrics, Eco-Friendly Laundry Soap
  • AUTHENTIC MARSEILLE SOAP – Crafted in France using traditional Marseille soap methods, slow-cooked for enhanced stain-removing power while remaining gentle on fabrics and fibers.
  • OVER 99% NATURAL, PLANT-BASED FORMULA - Powered by plant-based cleansers, olive and coconut-derived soaps, and biodegradable ingredients—free from PEG, MIT, and BIT preservatives.
  • POWERFUL CLEAN, EVEN IN COLD WATER - Concentrated formula effectively removes grease, dirt, and stains at low temperatures while preserving fabric color and integrity—ideal for energy-efficient washing.
  • HE COMPATIBLE & HIGHLY CONCENTRATED - Designed for high-efficiency machines with a low-sudsing, concentrated formula that delivers long-lasting performance with less product per wash.
  • GENTLE ON FABRICS, SAFE FOR THE FAMILY - Balanced with fiber-friendly ingredients and enzymes that break down stains while keeping clothes soft and wearable over time.
New
GLIDION Clothing Emulsifier Stain, Non-Ionic Laundry Pre-Treatment, Stain Remover for Oil, Sweat, Cosmetic & Food Stains, Active Enzyme Fabric Cleaner, 10 FL OZ (Pack of 1) 3PCS
  • POWERFUL NON-IONIC EMULSIFICATION: Our advanced non-ionic formula deeply penetrates fibers to emulsify and lift embedded oil, dirt, and grime that regular laundry detergent fails to remove. It effectively breaks down collar yellowing, cuff darkening, underarm sweat stains, cooking oil, makeup residue, food stains, and dairy stains to refresh and renew fabric appearance
  • ACTIVE ENZYME STAIN REMOVER: Fortified with a high-efficiency enzyme blend, this laundry pre-treatment targets protein, oil, and starch-based stains. It works on old, set-in stains and restores clothes to look fresh, bright, and clean without heavy scrubbing or repeated washing
  • GENTLE & SAFE FOR MOST FABRICS: Mild, low-irritation, non-bleaching, and non-corrosive formula protects fabric integrity. Ideal for daily use on cotton, linen, and synthetic fabrics. Low-foam design rinses easily, leaving no harmful residue while keeping clothes soft and durable
  • EASY 3-STEP PRE-WASH TREATMENT: Simply apply to dry stained areas, wait 2–5 minutes for penetration, gently rub, then wash as normal. Saves time and effort while reducing fabric damage from harsh brushing. Perfect for busy households, daily shirts, uniforms, and activewear
  • WIDELY USED & HIGHLY EFFICIENT: Designed as a professional pre-wash stain remover for home and daily use. Tackles the most common stubborn stains effortlessly. Suitable for adults’ and kids’ clothes, uniforms, casual wear, and heavily soiled items. Keep out of reach of children